| Gene: | VWF |
| GeneID: | ENSG00000110799 |
| Chrom: | 12 |
| Start position: | 5948877 |
| End position: | 6124770 |
| Pathway: | Complement and coagulation cascades |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.10231 |
| Number of nsSNPs: | 9 |
| nsSNPs in gene: | rs11063987 rs11063988 rs1800378 rs1800387 rs216311 rs2228317 rs2229446 rs57950734 rs78353028 |
| Gene Structure: |  |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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| Functional class: | Not specified |
| JensenLab PubMed score: | 9001.38 (Percentile rank: 99.65%) |
| PubTator score: | 5448.68 (Percentile rank: 99.53%) |
| Target development/druggability level: | TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |
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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital