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Table S1: The major geographically structured human populations from the 1000 Genomes Project used in this study.

Table S2. Summary of nsSNPs across major geographically structured human populations.

Table S3: List of nsSNPs that are globally rare (<0.5%) but common (>5%) in individual populations.

Table S4: Summary of FST values in nsSNPs based on Wright's F-statistics.

Table S5: List of KEGG pathways utilized in this study.

Table S6: Summary of genomic profiles in the TCGA dataset utilized in this study.

Table S7: Genes encoding proteins in the PRR pathways within the human genome.

Table S8: Cancer cell lines utilized in this study.

Table S9: Impact scores of nsSNPs within PRR-Genes.

Table S10: STING1 haplotypes in in human populations.

Table S11: GSEA for the upregulated genes identified by RNA-seq following treatment with cGAMP in isogenic SKOV3 cells.

Table S12: Summary of STING1 local ancestry across TCGA dataset.

Table S13: List of ID genes identified in this study.

Table S14: Gene Ontology (GO) analysis for the identified ID genes in tire 1.


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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital