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Description of image       
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      Gene:  TYK2
      GeneID:  ENSG00000105397
      Chrom:  19
      Start position:  10350533
      End position:  10380608
      Pathway:  JAK-STAT signaling pathway
      Class:  Environmental Information Processing; Signal transduction
      FST gene level:  0.0649958
      Number of nsSNPs:  1
      nsSNPs in gene:  rs2304256
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Kinase (protein kinase)
      JensenLab PubMed score:  252.91  (Percentile rank: 84.22%)
      PubTator score:  197.81  (Percentile rank: 85.78%)
      Target development/druggability level:  TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action.
      Tractability (small molecule):  Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital