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      Gene:  STAT3
      GeneID:  ENSG00000168610
      Chrom:  17
      Start position:  42313324
      End position:  42388568
      Pathway:  Chemokine signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0837673
      Number of nsSNPs:  2
      nsSNPs in gene:  rs149214040
rs2293152
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.20  
 
Recurrently deleted in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Transcription factor
      JensenLab PubMed score:  6459.66  (Percentile rank: 99.47%)
      PubTator score:  3667.37  (Percentile rank: 99.15%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  Predicted Tractable - Medium to low confidenceTargets with GO cell component terms plasma membrane or secreted with low or unknown confidence; Targets with predicted signal peptide and transmembrane domains; GO cell component - medium confidence; Human Protein Atlas - high confidence

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital