Description of image       

Description of image       
Search by Gene  



    
      Gene:  SHC1
      GeneID:  ENSG00000160691
      Chrom:  1
      Start position:  154962298
      End position:  154974395
      Pathway:  Chemokine signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.255047
      Number of nsSNPs:  1
      nsSNPs in gene:  rs8191979
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  1.47  (Driver)
Gscore (Del):  0.00  
 
Recurrently amplified in 6 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Not specified
      JensenLab PubMed score:  598.09  (Percentile rank: 92.16%)
      PubTator score:  478.28  (Percentile rank: 93.07%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Predicted TractableTargets with a predicted Ro5 druggable domain (druggable genome); Targets with a drugEBIlity score equal or greater than 0
      Tractability (antibody):  Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted

    

Contact us | | Terms & Conditions.
Copyright © 2024 University of Pennsylvania. All Rights Reserved.

Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital