| Gene: | SELPLG |
| GeneID: | ENSG00000110876 |
| Chrom: | 12 |
| Start position: | 108621895 |
| End position: | 108633894 |
| Pathway: | Neutrophil extracellular trap formation |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.0835458 |
| Number of nsSNPs: | 5 |
| nsSNPs in gene: | rs139716114 rs139943851 rs2228315 rs61729674 rs7300972 |
| Gene Structure: |  |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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| Functional class: | Not specified |
| JensenLab PubMed score: | 605.85 (Percentile rank: 92.26%) |
| PubTator score: | 650.00 (Percentile rank: 94.80%) |
| Target development/druggability level: | TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |
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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital