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      Gene:  RPS6KA4
      GeneID:  ENSG00000162302
      Chrom:  11
      Start position:  64359148
      End position:  64372215
      Pathway:  TNF signaling pathway
      Class:  Environmental Information Processing; Signal transduction
      FST gene level:  0.0923091
      Number of nsSNPs:  1
      nsSNPs in gene:  rs17857342
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.12  
Gscore (Del):  0.00  
 
Recurrently amplified in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Kinase (protein kinase)
      JensenLab PubMed score:  12.61  (Percentile rank: 40.01%)
      PubTator score:  9.22  (Percentile rank: 38.66%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital