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      Gene:  PRF1
      GeneID:  ENSG00000180644
      Chrom:  10
      Start position:  70597348
      End position:  70602759
      Pathway:  Natural killer cell mediated cytotoxicity
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0543335
      Number of nsSNPs:  1
      nsSNPs in gene:  rs35418374
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Not specified
      JensenLab PubMed score:  1546.28  (Percentile rank: 97.16%)
      PubTator score:  382.05  (Percentile rank: 91.55%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  Predicted Tractable - Medium to low confidenceTargets with GO cell component terms plasma membrane or secreted with low or unknown confidence; Targets with predicted signal peptide and transmembrane domains; GO cell component - medium confidence; Human Protein Atlas - high confidence

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital