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      Gene:  POLR3D
      GeneID:  ENSG00000168495
      Chrom:  8
      Start position:  22245133
      End position:  22254601
      Pathway:  Cytosolic DNA-sensing pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.111468
      Number of nsSNPs:  1
      nsSNPs in gene:  rs148812870
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  1.13  (Driver)
 
Recurrently deleted in 7 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Enzyme
      JensenLab PubMed score:  21.80  (Percentile rank: 48.86%)
      PubTator score:  8.70  (Percentile rank: 37.58%)
      Target development/druggability level:  TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
      Tractability (small molecule):  N/A
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital