| Gene: | PIK3R1 |
| GeneID: | ENSG00000145675 |
| Chrom: | 5 |
| Start position: | 68215740 |
| End position: | 68301821 |
| Pathway: | B cell receptor signaling pathway |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.0800253 |
| Number of nsSNPs: | 1 |
| nsSNPs in gene: | rs3730089 |
| Gene Structure: |  |
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Overall distribution
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Tissue specific distribution
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Overall distribution
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Tissue specific distribution
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| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.00 |
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| Recurrently deleted in 1 cancer type(s) |
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Overall distribution
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Tissue specific distribution
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| Recurrently mutated in 4 cancer type(s) |
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| Functional class: | Kinase |
| JensenLab PubMed score: | 316.35 (Percentile rank: 86.83%) |
| PubTator score: | 383.97 (Percentile rank: 91.59%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |