| Gene: | PDGFRB |
| GeneID: | ENSG00000113721 |
| Chrom: | 5 |
| Start position: | 150113839 |
| End position: | 150155872 |
| Pathway: | JAK-STAT signaling pathway |
| Class: | Environmental Information Processing; Signal transduction |
| FST gene level: | 0.0541182 |
| Number of nsSNPs: | 2 |
| nsSNPs in gene: | rs17110944 rs74943037 |
| Gene Structure: |  |
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
|
|
|
| |
|
|
|
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.00 |
|
|
|
| |
|
|
|
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
|
|
|
| |
|
|
|
| Functional class: | Kinase (protein kinase) |
| JensenLab PubMed score: | 712.31 (Percentile rank: 93.32%) |
| PubTator score: | 947.18 (Percentile rank: 96.31%) |
| Target development/druggability level: | TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action. |
| Tractability (small molecule): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |