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      Gene:  PARP1
      GeneID:  ENSG00000143799
      Chrom:  1
      Start position:  226360210
      End position:  226408154
      Pathway:  NF-kappa B signaling pathway
      Class:  Environmental Information Processing; Signal transduction
      FST gene level:  0.0865571
      Number of nsSNPs:  1
      nsSNPs in gene:  rs1136410
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.23  
 
Recurrently deleted in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.02  
 
Recurrently mutated in 1 cancer type(s)
   

    
      Functional class:  Enzyme
      JensenLab PubMed score:  4886.49  (Percentile rank: 99.24%)
      PubTator score:  4119.44  (Percentile rank: 99.30%)
      Target development/druggability level:  TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action.
      Tractability (small molecule):  Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital