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      Gene:  PAK6
      GeneID:  ENSG00000137843
      Chrom:  15
      Start position:  40217428
      End position:  40277487
      Pathway:  T cell receptor signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0988977
      Number of nsSNPs:  2
      nsSNPs in gene:  rs2412504
rs3743135
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.29  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Kinase (protein kinase)
      JensenLab PubMed score:  44.43  (Percentile rank: 60.49%)
      PubTator score:  28.56  (Percentile rank: 58.63%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital