| Gene: | P2RX7 |
| GeneID: | ENSG00000089041 |
| Chrom: | 12 |
| Start position: | 121132819 |
| End position: | 121188032 |
| Pathway: | NOD-like receptor signaling pathway |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.0822021 |
| Number of nsSNPs: | 6 |
| nsSNPs in gene: | rs1718119 rs208294 rs2230912 rs2230913 rs28360459 rs7958311 |
| Gene Structure: |  |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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Tissue specific distribution |
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| Functional class: | Ion channel |
| JensenLab PubMed score: | 962.24 (Percentile rank: 95.18%) |
| PubTator score: | 787.14 (Percentile rank: 95.60%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |
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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital