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      Gene:  ORAI1
      GeneID:  ENSG00000276045
      Chrom:  12
      Start position:  121626509
      End position:  121643218
      Pathway:  Platelet activation
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0712633
      Number of nsSNPs:  1
      nsSNPs in gene:  rs3741596
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.23  
 
Recurrently deleted in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Ion channel
      JensenLab PubMed score:  389.65  (Percentile rank: 88.81%)
      PubTator score:  352.88  (Percentile rank: 90.96%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital