| Gene: | OAS1 |
| GeneID: | ENSG00000089127 |
| Chrom: | 12 |
| Start position: | 112905856 |
| End position: | 112933219 |
| Pathway: | NOD-like receptor signaling pathway |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.0944622 |
| Number of nsSNPs: | 3 |
| nsSNPs in gene: | rs1131454 rs1131476 rs2660 |
| Gene Structure: |  |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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Tissue specific distribution |
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| Functional class: | Enzyme |
| JensenLab PubMed score: | 92.30 (Percentile rank: 71.48%) |
| PubTator score: | 89.30 (Percentile rank: 76.21%) |
| Target development/druggability level: | TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Predicted Tractable - Medium to low confidenceTargets with GO cell component terms plasma membrane or secreted with low or unknown confidence; Targets with predicted signal peptide and transmembrane domains; GO cell component - medium confidence; Human Protein Atlas - high confidence |
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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital