| Gene: | NOTCH1 |
| GeneID: | ENSG00000148400 |
| Chrom: | 9 |
| Start position: | 136494433 |
| End position: | 136546048 |
| Pathway: | Th1 and Th2 cell differentiation |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.122969 |
| Number of nsSNPs: | 1 |
| nsSNPs in gene: | rs61751489 |
| Gene Structure: |  |
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
|
|
|
| |
|
|
|
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.23 |
|
|
|
| |
|
|
|
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
|
|
| Recurrently mutated in 2 cancer type(s) |
|
| |
|
|
|
| Functional class: | Not specified |
| JensenLab PubMed score: | 11843.16 (Percentile rank: 99.77%) |
| PubTator score: | 1380.97 (Percentile rank: 97.48%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |