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      Gene:  NOD2
      GeneID:  ENSG00000167207
      Chrom:  16
      Start position:  50693588
      End position:  50733077
      Pathway:  NOD-like receptor signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.101127
      Number of nsSNPs:  3
      nsSNPs in gene:  rs2066842
rs5743278
rs5743291
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Not specified
      JensenLab PubMed score:  1445.51  (Percentile rank: 96.97%)
      PubTator score:  1555.79  (Percentile rank: 97.74%)
      Target development/druggability level:  TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action.
      Tractability (small molecule):  Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets
      Tractability (antibody):  Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital