| Gene: | NLRP1 |
| GeneID: | ENSG00000091592 |
| Chrom: | 17 |
| Start position: | 5499415 |
| End position: | 5619424 |
| Pathway: | NOD-like receptor signaling pathway |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.0959062 |
| Number of nsSNPs: | 6 |
| nsSNPs in gene: | rs115872694 rs12150220 rs146932154 rs2137722 rs2301582 rs73973843 |
| Gene Structure: |  |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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| Functional class: | Not specified |
| JensenLab PubMed score: | 116.48 (Percentile rank: 74.87%) |
| PubTator score: | 102.03 (Percentile rank: 78.00%) |
| Target development/druggability level: | TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): |
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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital