| Gene: | MYLK |
| GeneID: | ENSG00000065534 |
| Chrom: | 3 |
| Start position: | 123610049 |
| End position: | 123884332 |
| Pathway: | Platelet activation |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.163487 |
| Number of nsSNPs: | 6 |
| nsSNPs in gene: | rs143896146 rs28497577 rs3732486 rs3732487 rs75370906 rs9840993 |
| Gene Structure: |  |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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Tissue specific distribution |
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| Functional class: | Kinase (protein kinase) |
| JensenLab PubMed score: | 693.95 (Percentile rank: 93.17%) |
| PubTator score: | 649.69 (Percentile rank: 94.78%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |
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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital