| Gene: | MMP14 |
| GeneID: | ENSG00000157227 |
| Chrom: | 14 |
| Start position: | 22836560 |
| End position: | 22849041 |
| Pathway: | TNF signaling pathway |
| Class: | Environmental Information Processing; Signal transduction |
| FST gene level: | 0.0734842 |
| Number of nsSNPs: | 2 |
| nsSNPs in gene: | rs1042704 rs17879780 |
| Gene Structure: |  |
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| Expression restricted in 1 cancer type(s) |
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Tissue specific distribution
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| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.00 |
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Tissue specific distribution
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| Functional class: | Enzyme |
| JensenLab PubMed score: | 1087.86 (Percentile rank: 95.74%) |
| PubTator score: | 978.64 (Percentile rank: 96.42%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |