Description of image       

Description of image       
Search by Gene  



    
      Gene:  MMP14
      GeneID:  ENSG00000157227
      Chrom:  14
      Start position:  22836560
      End position:  22849041
      Pathway:  TNF signaling pathway
      Class:  Environmental Information Processing; Signal transduction
      FST gene level:  0.0734842
      Number of nsSNPs:  2
      nsSNPs in gene:  rs1042704
rs17879780
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
Expression restricted in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Enzyme
      JensenLab PubMed score:  1087.86  (Percentile rank: 95.74%)
      PubTator score:  978.64  (Percentile rank: 96.42%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted

    

Contact us | | Terms & Conditions.
Copyright © 2024 University of Pennsylvania. All Rights Reserved.

Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital