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      Gene:  MAPK4
      GeneID:  ENSG00000141639
      Chrom:  18
      Start position:  50560087
      End position:  50731826
      Pathway:  IL-17 signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0466171
      Number of nsSNPs:  1
      nsSNPs in gene:  rs3752087
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Kinase (protein kinase)
      JensenLab PubMed score:  13.78  (Percentile rank: 41.27%)
      PubTator score:  15.57  (Percentile rank: 47.67%)
      Target development/druggability level:  TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital