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Description of image       
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      Gene:  MAPK15
      GeneID:  ENSG00000181085
      Chrom:  8
      Start position:  143716340
      End position:  143722458
      Pathway:  IL-17 signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.158271
      Number of nsSNPs:  3
      nsSNPs in gene:  rs576245505
rs34410761
rs60732298
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.93  (Driver)
Gscore (Del):  0.00  
 
Recurrently amplified in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Kinase (protein kinase)
      JensenLab PubMed score:  34.46  (Percentile rank: 56.32%)
      PubTator score:  18.36  (Percentile rank: 50.69%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital