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      Gene:  MAP3K1
      GeneID:  ENSG00000095015
      Chrom:  5
      Start position:  56815549
      End position:  56896152
      Pathway:  RIG-I-like receptor signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.085293
      Number of nsSNPs:  1
      nsSNPs in gene:  rs702689
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.24  
 
Recurrently deleted in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.48  (Driver)
 
Recurrently mutated in 2 cancer type(s)
   

    
      Functional class:  Kinase (protein kinase)
      JensenLab PubMed score:  119.44  (Percentile rank: 75.19%)
      PubTator score:  172.34  (Percentile rank: 84.38%)
      Target development/druggability level:  TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
      Tractability (small molecule):  Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital