| Gene: | LEPR |
| GeneID: | ENSG00000116678 |
| Chrom: | 1 |
| Start position: | 65420652 |
| End position: | 65641559 |
| Pathway: | Cytokine-cytokine receptor interaction |
| Class: | Environmental Information Processing; Signaling molecules and interaction |
| FST gene level: | 0.170335 |
| Number of nsSNPs: | 2 |
| nsSNPs in gene: | rs1137100 rs1137101 |
| Gene Structure: |  |
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
|
|
|
| |
|
|
|
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.00 |
|
|
|
| |
|
|
|
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
|
|
| Recurrently mutated in 1 cancer type(s) |
|
| |
|
|
|
| Functional class: | Not specified |
| JensenLab PubMed score: | 782.63 (Percentile rank: 94.01%) |
| PubTator score: | 736.45 (Percentile rank: 95.37%) |
| Target development/druggability level: | TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |