| Gene: | KLKB1 |
| GeneID: | ENSG00000164344 |
| Chrom: | 4 |
| Start position: | 186226438 |
| End position: | 186258471 |
| Pathway: | Complement and coagulation cascades |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.0566563 |
| Number of nsSNPs: | 2 |
| nsSNPs in gene: | rs3733402 rs4253379 |
| Gene Structure: |  |
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
|
|
|
| |
|
|
|
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.00 |
|
|
|
| |
|
|
|
| |
Overall distribution
|
|
Tissue specific distribution
|
| |
|
|
|
| |
|
|
|
| Functional class: | Enzyme |
| JensenLab PubMed score: | 720.11 (Percentile rank: 93.39%) |
| PubTator score: | 111.16 (Percentile rank: 79.13%) |
| Target development/druggability level: | TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |