| Gene: | JAK3 |
| GeneID: | ENSG00000105639 |
| Chrom: | 19 |
| Start position: | 17824780 |
| End position: | 17848071 |
| Pathway: | Chemokine signaling pathway |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.0811351 |
| Number of nsSNPs: | 1 |
| nsSNPs in gene: | rs3212723 |
| Gene Structure: |  |
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| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.00 |
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| Functional class: | Kinase (protein kinase) |
| JensenLab PubMed score: | 453.65 (Percentile rank: 90.16%) |
| PubTator score: | 330.40 (Percentile rank: 90.49%) |
| Target development/druggability level: | TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action. |
| Tractability (small molecule): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |
