Description of image       

Description of image       
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      Gene:  ITGB2
      GeneID:  ENSG00000160255
      Chrom:  21
      Start position:  44885953
      End position:  44931989
      Pathway:  Complement and coagulation cascades
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0875322
      Number of nsSNPs:  1
      nsSNPs in gene:  rs201802601
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.05  
 
Recurrently mutated in 1 cancer type(s)
   

    
      Functional class:  Not specified
      JensenLab PubMed score:  232.11  (Percentile rank: 83.39%)
      PubTator score:  1246.23  (Percentile rank: 97.19%)
      Target development/druggability level:  TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital