| Gene: | IRAK4 |
| GeneID: | ENSG00000198001 |
| Chrom: | 12 |
| Start position: | 43758944 |
| End position: | 43798307 |
| Pathway: | NF-kappa B signaling pathway |
| Class: | Environmental Information Processing; Signal transduction |
| FST gene level: | 0.101036 |
| Number of nsSNPs: | 1 |
| nsSNPs in gene: | rs4251545 |
| Gene Structure: |  |
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| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.00 |
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| Functional class: | Kinase (protein kinase) |
| JensenLab PubMed score: | 202.19 (Percentile rank: 81.85%) |
| PubTator score: | 133.07 (Percentile rank: 81.44%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |