Description of image       

Description of image       
Search by Gene  



    
      Gene:  INPPL1
      GeneID:  ENSG00000165458
      Chrom:  11
      Start position:  72223701
      End position:  72239147
      Pathway:  B cell receptor signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0500969
      Number of nsSNPs:  2
      nsSNPs in gene:  rs11548491
rs17847215
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.88  (Driver)
Gscore (Del):  0.10  
 
Recurrently amplified in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.43  (Driver)
 
Recurrently mutated in 2 cancer type(s)
   

    
      Functional class:  Enzyme
      JensenLab PubMed score:  144.21  (Percentile rank: 77.68%)
      PubTator score:  126.35  (Percentile rank: 80.79%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  Predicted Tractable - Medium to low confidenceTargets with GO cell component terms plasma membrane or secreted with low or unknown confidence; Targets with predicted signal peptide and transmembrane domains; GO cell component - medium confidence; Human Protein Atlas - high confidence

    

Contact us | | Terms & Conditions.
Copyright © 2024 University of Pennsylvania. All Rights Reserved.

Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital