| Gene: | IL6ST |
| GeneID: | ENSG00000134352 |
| Chrom: | 5 |
| Start position: | 55935095 |
| End position: | 55995022 |
| Pathway: | Cytokine-cytokine receptor interaction |
| Class: | Environmental Information Processing; Signaling molecules and interaction |
| FST gene level: | 0.16081 |
| Number of nsSNPs: | 3 |
| nsSNPs in gene: | rs2228043
rs2228044
rs2228046 |
| Gene Structure: |  |
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Overall distribution
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| Gscore (Amp): | 0.00 | | Gscore (Del): | 0.24 |
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| Recurrently deleted in 1 cancer type(s) |
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| Recurrently mutated in 1 cancer type(s) |
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| Functional class: | Not specified |
| JensenLab PubMed score: | 55.35 (Percentile rank: 64.04%) |
| PubTator score: | 439.23 (Percentile rank: 92.49%) |
| Target development/druggability level: | TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action. |
| Tractability (small molecule): | Predicted TractableTargets with a predicted Ro5 druggable domain (druggable genome); Targets with a drugEBIlity score equal or greater than 0 |
| Tractability (antibody): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |
