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      Gene:  IL6R
      GeneID:  ENSG00000160712
      Chrom:  1
      Start position:  154405193
      End position:  154469450
      Pathway:  Cytokine-cytokine receptor interaction
      Class:  Environmental Information Processing; Signaling molecules and interaction
      FST gene level:  0.0700163
      Number of nsSNPs:  1
      nsSNPs in gene:  rs2228146
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.22  
Gscore (Del):  0.00  
 
Recurrently amplified in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Not specified
      JensenLab PubMed score:  271.64  (Percentile rank: 85.09%)
      PubTator score:  675.74  (Percentile rank: 95.02%)
      Target development/druggability level:  TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital