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      Gene:  IKBKE
      GeneID:  ENSG00000263528
      Chrom:  1
      Start position:  206470476
      End position:  206496889
      Pathway:  C-type lectin receptor signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0995009
      Number of nsSNPs:  2
      nsSNPs in gene:  rs12059562
rs3748022
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.12  
Gscore (Del):  0.00  
 
Recurrently amplified in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Kinase (protein kinase)
      JensenLab PubMed score:  43.02  (Percentile rank: 60.00%)
      PubTator score:  70.65  (Percentile rank: 73.14%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital