| Gene: | HLA-DQB1 |
| GeneID: | ENSG00000179344 |
| Chrom: | 6 |
| Start position: | 32659467 |
| End position: | 32668383 |
| Pathway: | Antigen processing and presentation |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.0341908 |
| Number of nsSNPs: | 5 |
| nsSNPs in gene: | rs281874782 rs1130429 rs12722106 rs12722107 rs36222416 |
| Gene Structure: |  |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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| Functional class: | Not specified |
| JensenLab PubMed score: | 564.49 (Percentile rank: 91.75%) |
| PubTator score: | 486.31 (Percentile rank: 93.16%) |
| Target development/druggability level: | TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |
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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital