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      Gene:  HGS
      GeneID:  ENSG00000185359
      Chrom:  17
      Start position:  81683326
      End position:  81703138
      Pathway:  Viral life cycle - HIV-1
      Class:  Genetic Information Processing; Information processing in viruses
      FST gene level:  0.0514357
      Number of nsSNPs:  2
      nsSNPs in gene:  rs1128805
rs56058441
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.77  (Driver)
Gscore (Del):  0.00  
 
Recurrently amplified in 3 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Enzyme
      JensenLab PubMed score:  560.08  (Percentile rank: 91.70%)
      PubTator score:  51.28  (Percentile rank: 68.25%)
      Target development/druggability level:  TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital