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      Gene:  GRK4
      GeneID:  ENSG00000125388
      Chrom:  4
      Start position:  2963571
      End position:  3040760
      Pathway:  Chemokine signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0975253
      Number of nsSNPs:  3
      nsSNPs in gene:  rs1024323
rs1801058
rs2960306
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Kinase (protein kinase)
      JensenLab PubMed score:  54.82  (Percentile rank: 63.82%)
      PubTator score:  76.99  (Percentile rank: 74.35%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital