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      Gene:  GAB2
      GeneID:  ENSG00000033327
      Chrom:  11
      Start position:  78215293
      End position:  78418348
      Pathway:  Fc epsilon RI signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0801803
      Number of nsSNPs:  2
      nsSNPs in gene:  rs74817689
rs76853537
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  1.19  (Driver)
Gscore (Del):  0.00  
 
Recurrently amplified in 3 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Not specified
      JensenLab PubMed score:  139.78  (Percentile rank: 77.17%)
      PubTator score:  105.84  (Percentile rank: 78.52%)
      Target development/druggability level:  TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
      Tractability (small molecule):  N/A
      Tractability (antibody):  Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital