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      Gene:  FURIN
      GeneID:  ENSG00000140564
      Chrom:  15
      Start position:  90868588
      End position:  90883564
      Pathway:  Viral life cycle - HIV-1
      Class:  Genetic Information Processing; Information processing in viruses
      FST gene level:  0.123285
      Number of nsSNPs:  1
      nsSNPs in gene:  rs16944971
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.70  (Driver)
Gscore (Del):  0.00  
 
Recurrently amplified in 4 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Enzyme
      JensenLab PubMed score:  1183.48  (Percentile rank: 96.19%)
      PubTator score:  782.58  (Percentile rank: 95.57%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital