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      Gene:  F10
      GeneID:  ENSG00000126218
      Chrom:  13
      Start position:  113122799
      End position:  113149529
      Pathway:  Complement and coagulation cascades
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0613128
      Number of nsSNPs:  2
      nsSNPs in gene:  rs3211783
rs5961
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
Expression restricted in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.80  (Driver)
Gscore (Del):  0.00  
 
Recurrently amplified in 4 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Enzyme
      JensenLab PubMed score:  1386.92  (Percentile rank: 96.82%)
      PubTator score:  3139.95  (Percentile rank: 99.01%)
      Target development/druggability level:  TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action.
      Tractability (small molecule):  Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets
      Tractability (antibody):  Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital