Description of image       

Description of image       
Search by Gene  



    
      Gene:  EP300
      GeneID:  ENSG00000100393
      Chrom:  22
      Start position:  41092510
      End position:  41180077
      Pathway:  JAK-STAT signaling pathway
      Class:  Environmental Information Processing; Signal transduction
      FST gene level:  0.108996
      Number of nsSNPs:  1
      nsSNPs in gene:  rs20551
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.33  
Gscore (Del):  0.00  
 
Recurrently amplified in 1 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  1.58  (Driver)
 
Recurrently mutated in 7 cancer type(s)
   

    
      Functional class:  Epigenetic
      JensenLab PubMed score:  6016.68  (Percentile rank: 99.39%)
      PubTator score:  3116.19  (Percentile rank: 98.99%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  

    

Contact us | | Terms & Conditions.
Copyright © 2024 University of Pennsylvania. All Rights Reserved.

Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital