| Gene: | CTSB |
| GeneID: | ENSG00000164733 |
| Chrom: | 8 |
| Start position: | 11842524 |
| End position: | 11869533 |
| Pathway: | Antigen processing and presentation |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.0504364 |
| Number of nsSNPs: | 2 |
| nsSNPs in gene: | rs17573 rs1803250 |
| Gene Structure: |  |
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Overall distribution
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Tissue specific distribution
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| Expression restricted in 1 cancer type(s) |
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Overall distribution
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Tissue specific distribution
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| Gscore (Amp): | 0.54 | | Gscore (Del): | 0.39 |
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| Recurrently amplified in 1 cancer type(s) | | Recurrently deleted in 3 cancer type(s) |
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Overall distribution
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Tissue specific distribution
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| Functional class: | Enzyme |
| JensenLab PubMed score: | 5011.47 (Percentile rank: 99.27%) |
| PubTator score: | 2020.79 (Percentile rank: 98.35%) |
| Target development/druggability level: | TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |