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      Gene:  CTLA4
      GeneID:  ENSG00000163599
      Chrom:  2
      Start position:  203853888
      End position:  203873965
      Pathway:  T cell receptor signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0633092
      Number of nsSNPs:  1
      nsSNPs in gene:  rs231775
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Not specified
      JensenLab PubMed score:  3949.07  (Percentile rank: 99.01%)
      PubTator score:  2511.15  (Percentile rank: 98.73%)
      Target development/druggability level:  TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital