| Gene: | CR1 |
| GeneID: | ENSG00000203710 |
| Chrom: | 1 |
| Start position: | 207496147 |
| End position: | 207641765 |
| Pathway: | Complement and coagulation cascades |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.126224 |
| Number of nsSNPs: | 9 |
| nsSNPs in gene: | rs149099494 rs17047660 rs17047661 rs17259045 rs2274567 rs3737002 rs3811381 rs61730889 rs6691117 |
| Gene Structure: |  |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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| Functional class: | Not specified |
| JensenLab PubMed score: | 2362.61 (Percentile rank: 98.29%) |
| PubTator score: | 1220.04 (Percentile rank: 97.13%) |
| Target development/druggability level: | TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code. |
| Tractability (small molecule): | N/A |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |
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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital