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      Gene:  CHRNA1
      GeneID:  ENSG00000138435
      Chrom:  2
      Start position:  174747592
      End position:  174787935
      Pathway:  Virion - Lyssavirus
      Class:  Genetic Information Processing; Information processing in viruses
      FST gene level:  0.115119
      Number of nsSNPs:  1
      nsSNPs in gene:  rs6739001
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Ion channel
      JensenLab PubMed score:  41.70  (Percentile rank: 59.44%)
      PubTator score:  99.37  (Percentile rank: 77.59%)
      Target development/druggability level:  TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action.
      Tractability (small molecule):  Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets
      Tractability (antibody):  Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital