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      Gene:  CDKN1A
      GeneID:  ENSG00000124762
      Chrom:  6
      Start position:  36676460
      End position:  36687337
      Pathway:  JAK-STAT signaling pathway
      Class:  Environmental Information Processing; Signal transduction
      FST gene level:  0.0634681
      Number of nsSNPs:  1
      nsSNPs in gene:  rs1801270
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.27  (Driver)
 
Recurrently mutated in 1 cancer type(s)
   

    
      Functional class:  Enzyme
      JensenLab PubMed score:  3042.80  (Percentile rank: 98.67%)
      PubTator score:  3747.94  (Percentile rank: 99.16%)
      Target development/druggability level:  TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
      Tractability (small molecule):  Predicted TractableTargets with a predicted Ro5 druggable domain (druggable genome); Targets with a drugEBIlity score equal or greater than 0
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital