| Gene: | CASR |
| GeneID: | ENSG00000036828 |
| Chrom: | 3 |
| Start position: | 122183668 |
| End position: | 122291629 |
| Pathway: | NOD-like receptor signaling pathway |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.109437 |
| Number of nsSNPs: | 4 |
| nsSNPs in gene: | rs1042636 rs12493789 rs1801725 rs1801726 |
| Gene Structure: |  |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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Tissue specific distribution |
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| Functional class: | G protein-coupled receptor |
| JensenLab PubMed score: | 1714.87 (Percentile rank: 97.48%) |
| PubTator score: | 875.21 (Percentile rank: 95.95%) |
| Target development/druggability level: | TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action. |
| Tractability (small molecule): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |
| Tractability (antibody): | Predicted Tractable - High confidenceTargets located in the plasma membrane; Targets with GO cell component terms plasma membrane or secreted |
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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital