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      Gene:  CASP5
      GeneID:  ENSG00000137757
      Chrom:  11
      Start position:  104994235
      End position:  105023168
      Pathway:  NOD-like receptor signaling pathway
      Class:  Organismal Systems; Immune system
      FST gene level:  0.0810556
      Number of nsSNPs:  5
      nsSNPs in gene:  rs3181179
rs3181320
rs45608432
rs507879
rs523104
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.00  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Enzyme
      JensenLab PubMed score:  96.05  (Percentile rank: 72.07%)
      PubTator score:  13.90  (Percentile rank: 45.80%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital