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      Gene:  CARD14
      GeneID:  ENSG00000141527
      Chrom:  17
      Start position:  80169992
      End position:  80216073
      Pathway:  NF-kappa B signaling pathway
      Class:  Environmental Information Processing; Signal transduction
      FST gene level:  0.0485149
      Number of nsSNPs:  4
      nsSNPs in gene:  rs11652075
rs11653893
rs2289541
rs34850974
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  1.08  (Driver)
Gscore (Del):  0.00  
 
Recurrently amplified in 4 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  0.00  
 
   

    
      Functional class:  Enzyme
      JensenLab PubMed score:  42.91  (Percentile rank: 59.94%)
      PubTator score:  54.57  (Percentile rank: 69.35%)
      Target development/druggability level:  TbioThese targets do not have known drug or small molecule activities that satisfy the activity thresholds detailed below AND satisfy one or more of the following criteria: 1) target is above the cutoff criteria for Tdark; 2) target is annotated with a Gene Ontology Molecular Function or Biological Process leaf term(s) with an Experimental Evidence code.
      Tractability (small molecule):  N/A
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital