| Gene: | C5 |
| GeneID: | ENSG00000106804 |
| Chrom: | 9 |
| Start position: | 120932987 |
| End position: | 121075195 |
| Pathway: | Complement and coagulation cascades |
| Class: | Organismal Systems; Immune system |
| FST gene level: | 0.110258 |
| Number of nsSNPs: | 6 |
| nsSNPs in gene: | rs17216529 rs17610 rs17611 rs2230212 rs2230213 rs41311887 |
| Gene Structure: |  |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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Overall distribution |
Tissue specific distribution |
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| Functional class: | Not specified |
| JensenLab PubMed score: | 170.79 (Percentile rank: 79.83%) |
| PubTator score: | 938.83 (Percentile rank: 96.28%) |
| Target development/druggability level: | TclinThese targets have activities in DrugCentral (ie. approved drugs) with known mechanism of action. |
| Tractability (small molecule): | Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands |
| Tractability (antibody): | Clinical PrecedenceTargets with drugs in phase II or above; Pre-clinical targets |
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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital