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Description of image       
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      Gene:  ATM
      GeneID:  ENSG00000149311
      Chrom:  11
      Start position:  108222804
      End position:  108369102
      Pathway:  NF-kappa B signaling pathway
      Class:  Environmental Information Processing; Signal transduction
      FST gene level:  0.0769422
      Number of nsSNPs:  6
      nsSNPs in gene:  rs1801516
rs2227924
rs2234997
rs2235000
rs3092857
rs3218673
      Gene Structure:  

    

    
  Overall distribution
    
  Tissue specific distribution
    
 
  
 
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Gscore (Amp):  0.00  
Gscore (Del):  0.44  
 
Recurrently deleted in 4 cancer type(s)
   

    
  Overall distribution
    
  Tissue specific distribution
    
 
Mscore:  1.10  (Driver)
 
Recurrently mutated in 6 cancer type(s)
   

    
      Functional class:  Kinase (protein kinase)
      JensenLab PubMed score:  3681.59  (Percentile rank: 98.93%)
      PubTator score:  1885.93  (Percentile rank: 98.20%)
      Target development/druggability level:  TchemThese targets have activities in ChEMBL or DrugCentral that satisfy the activity thresholds detailed below.
      Tractability (small molecule):  Discovery PrecedenceTargets with ligands; Targets with crystal structures with ligands
      Tractability (antibody):  

    

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Data portal developer
Yuxin Wang MD, PhD
University of Pennsylvania School of Medicine
Peking Union Medical College Hospital